This is the planetary nebula NGC 246, aka the Skull Nebula, in Cetus, a planetary with a structured disk and a 12th magnitude central star. It is about 1600 light years away. Just above it is the galaxy NGC 255. Just to the right of that spiral galaxy and below a bright star is the odd-looking 14th-magnitude spiral galaxy PGC 2689.
Technical:
This is a stack of 16 x 4 minute exposures with the Askar APO120 refractor at f/5.6 with its 0.8x Reducer, with the Canon Ra at ISO 1600. Taken from the Quailway Cottage in southern Arizona on an astrophoto junket in October 2024.